Oscorp, also known as Oscorp Industries, is an American multinational corporation appearing in Marvel's Spider-Man series. Norman Osborn is the CEO of Oscorp, who co-founded the company with Otto Octavius.
Oscorp was founded by Norman Osborn and Otto Octavius, who met in graduate school. The name for the company was inspired by "the O's", Osborn and Octavius's nicknames in college.
Unfortunately, due to the death of Norman’s wife Emily, and the same disease which killed her will occur to his son Harry, then the Devil's Breath project resulted the creation of Mister Negative, which killed his parents as a child, there has been a fallout between two Oscorp founders, resulting Otto quit the company, and created his own out of guilt.
Oscorp use to have had a Science Center at Upper West Side, but was not present in the first game. Miles Morales and the Mason siblings won the award for the energy converter in this center, which would become the main inspiration for the Nuform. Harry's friend Peter Parker, and even Otto were also there to find the material concepts for their prosthetic projects.
After being elected mayor, Osborn remained the CEO of Oscorp, and had the company's technology integrated throughout the city, including in surveillance tech.
Oscorp Science Center, which had been long closed by the time of the first game's event occurred was announced by Oscorp to be renovated. Before the renovation starts, the Underground use it as one of its hideouts.
Ganke Lee hack into Oscorp's security cameras at Harlem to help Rio Morales to evacuate the citizens from the town, by the time when the Underground and Roxxon about to turn it into a battleground, whereas the former faction begin to make a move to destroy the plaza, and would unwittingly destroy the town along with it with a stolen Nuform canister on the plaza's reactor.
Oscorp first appeared in Amazing Spider-Man #37 (June 1966).